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. 2013 Jul 4;10(9):1113–1120. doi: 10.7150/ijms.6843

Table 1.

Characteristics of studies included in the meta-analysis.

Study Year Country Ethnicity Case Control PHWE NOS
WT Ho Ht VR Ho WT Ho Ht VR Ho
rs1501299G/T GG GT TT GG GT TT
Al-Harithy7 2012 Saudi Arabia Asian 55 5* 58 2* NA 5
He9 2011 China Asian 220 160 40 265 224 66 0.08 7
Kaklamani10 2008 USA Caucasian 208 180 45 285 293 58 0.16 9
Keku11 2012 USA Caucasian 122 106 27 223 204 36 0.25 8
Keku TO11 2012 USA African-American 78 94 19 116 119 41 0.25 8
Partida-Perez12 2010 Mexico Caucasian 51 40 3 30 25 3 0.44 7
Tsilidis14 2009 USA Caucasian 96 86 19 198 134 27 0.51 8
Zhang15 2012 China Asian 196 139 35 174 152 44 0.23 7
rs2241766T/G TT TG GG TT TG GG
Al-Harithy7 2012 Saudi Arabia Asian 40 20* 27 33* NA 5
He9 2011 China Asian 190 193 37 278 238 39 0.21 8
Kaklamani10 2008 USA Caucasian 279 141 20 435 172 41 <0.01 9
Partida-Perez12 2010 Mexico Caucasian 74 34 3 42 16 0 0.22 6
Zhang15 2012 China Asian 167 172 31 186 158 26 0.33 7
rs266729C/G CC CG GG CC CG GG
Gornick8 2011 Israel Asian 576 486* 588 474* NA 6
He9 2011 China Asian 173 205 42 243 261 51 0.11 7
Kaklamani10 2008 USA Caucasian 244 163 27 340 271 47 0.48 8
Pechlivanis13 2009 Czech Caucasian 366 238 55 373 278 65 0.21 8
Zhang15 2012 China Asian 146 185 39 162 172 36 0.32 7
rs822395A/C AA AC CC AA AC CC
He9 2011 China Asian 343 70 7 440 109 6 0.79 7
Kaklamani10 2008 USA Caucasian 184 202 45 301 265 88 0.02 6
Zhang15 2012 China Asian 299 66 5 294 72 4 0.86 7
rs822396A/G AA AG GG AA AG GG
He9 2011 China Asian 344 73 3 450 99 6 0.83 7
Kaklamani10 2008 USA Caucasian 305 114 13 477 157 16 0.48 8
Zhang15 2012 China Asian 300 67 3 300 66 4 0.86 7

HWE, Hardy-Weinberg equilibrium; PHWE was calculated by goodness-of fit χ2-test, PHWE < 0.05 was considered statistically significant; NA, not available. Ht, heterozygote; VR Ho, variant homozygote; WT Ho, wide-type homozygote; * Numbers of Ht+ VR Ho; NOS, Newcastle-Ottawa Scale.