Table 4.
lists the first 13 of the 57 most affected genes which show read counts solely in the lamin B1 probe but not in the H2A-KRED control (schematized shown in Table 6, which demonstrates their possible spatial intranuclear localization). The right column describes the physical mapping of the chromosomal regions.
| Refseq ID | Read Counts | Gene Symbol | Description | Physical map |
|---|---|---|---|---|
| NM_001127482 | 12550 | SPRYD7 | SPRY domain containing 7 | 13q14.2 [R] |
| NM_001003796 | 6584 | NHP2L1 | non-histone chromosome protein 2-like 1 | 22q13.2 [G] |
| NM_001039210 | 6428 | ALG13 | asparagine-linked glycosylation 13 homolog | Xq23 [G] |
| NM_001004333 | 6331 | RNASEK | RNase kappa | 17p13.1 [R] |
| NM_001035223 | 5688 | RGL3 | Ral guanine nucleotide dissoc stimul-like 3 | 19p13.2 [G] |
| NM_001114106 | 5055 | SLC44A3 | solute carrier family 44, member 3 | 1p21.3 [G] |
| NM_001099410 | 4953 | GPRASP1 | G-protein coupled receptor-assoc sort protein 1 | Xq22.1 [R] |
| NM_001105538 | 4826 | MYBBP1A | myb-binding protein 1A | 17p13.2 [G] |
| NM_001124759 | 4339 | FRG2C | FSHD region gene 2 family, member C | 3p12.3 [G] |
| NM_001099455 | 4305 | CPPED1 | calcineurin-like phosphoesterase dom protein 1 | 16p13.12 [G] |
| NM_001171799 | 3906 | TRIQK | Triple QxxK/R motif-containing protein | 8q22.1 [R] |
| NM_001134364 | 3613 | MAP4 | microtubule-associated protein 4 | 3p21.31 [R] |
| NM_001139518 | 3409 | PRKRA | protein kinase interferon-inducible ds RNA dependent | 2q31.2 [G] |