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Esophagogastric junction (EGJ) outflow obstruction is characterized by failed or incomplete opening of the EGJ (integrated relaxation or residual pressure [IRP] greater than normal), some peristalsis in the smooth muscle esophagus and pressurization of the swallowed bolus between an unyielding EGJ and peristaltic contraction (arrowhead). Peristalsis can be normal, weak, hypertensive or hypercontractile. UES, upper esophageal sphincter.
