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A–C) Renal mRNA expression of inflammatory markers IL-1β (A), IL-6 (B), and TNF-α (C) in cisplatin-treated rats pretreated with either EET analogs (EET-A and EET-B) or vehicle. D, E) Urinary MCP-1 (D) and renal tissue levels of TNF-α (E) in cisplatin-treated rats pretreated with either EET analogs or vehicle. Data are expressed as means ± sem, n = 5–7. *P < 0.05 vs. normal WKY rat; #P < 0.05 vs. vehicle-pretreated rat administered cisplatin.
