Table 1.
Results of Mann-Whitney tests to evaluate differences in distribution of Δ[AA] between eukaryotes and prokaryotes
| Residue | Eukaryotes | Prokaryotes | U | P | U/mn |
|---|---|---|---|---|---|
| A | −2.01 | −0.29 | 3,484,667 | 6.3 × 10−56 | 0.38 |
| V | −0.03 | −0.13 | 4,692,108 | 1.4 × 10−1 | 0.51 |
| L | 1.27 | 1.53 | 4,494,450 | 1.8 × 10−1 | 0.49 |
| I | −0.29 | −0.61 | 4,845,335 | 2.4 × 10−4 | 0.53 |
| M | −0.32 | −0.44 | 4,781,449 | 5.7 × 10−3 | 0.52 |
| F | 0.53 | 0.06 | 5,019,341 | 7.3 × 10−10 | 0.55 |
| Y | −0.27 | −1.00 | 5,564,109 | 3.6 × 10−44 | 0.61 |
| W | −0.46 | −0.92 | 5,529,692 | 3.2 × 10−41 | 0.60 |
| S | −0.47 | −0.18 | 4,329,195 | 2.2 × 10−4 | 0.47 |
| T | −1.36 | −0.07 | 3,616,488 | 9.2 × 10−44 | 0.39 |
| N | −1.63 | −1.86 | 4,339,854 | 3.9 × 10−4 | 0.47 |
| Q | 1.11 | 1.49 | 4,198,344 | 2.6 × 10−8 | 0.46 |
| C | −1.25 | −0.28 | 2,881,834 | 7.5 × 10−132 | 0.31 |
| G | −5.2 | −5.3 | 4,576,112 | 8.7 × 10−1 | 0.50 |
| P | −0.67 | 0.04 | 3,852,582 | 8.5 × 10−26 | 0.42 |
| D | −0.25 | −1.52 | 5,644,738 | 1.9 × 10−51 | 0.62 |
| E | 2.85 | 2.51 | 4,864,907 | 7.7 × 10−5 | 0.53 |
| H | 1.53 | −0.56 | 7,048,731 | 1.6 × 10−270 | 0.77 |
| K | 1.45 | 1.58 | 4,356,812 | 9.6 × 10−4 | 0.47 |
| R | 1.86 | 0.95 | 5,376,156 | 2.2 × 10−29 | 0.59 |
For each amino acid, the following numbers are reported: median of Δ[AA] for eukaryotes and prokaryotes, test statistic of the Mann-Whitney test, the resulting P value, and the effect size U/mn. Sample sizes were 2156 and 4256 for eukaryotes and prokaryotes, respectively.