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. 2013 Jan;1832(1):160–173. doi: 10.1016/j.bbadis.2012.10.011

Fig. 8.

Fig. 8

Fig. 8

Strumpellin depletion, but not mutation, alters the distribution of SNX27 and β2AR. (A–D) HeLa cells were subjected to mock siRNA transfection (A and C) or were transfected with siRNA versus strumpellin (B and D), and in addition were transfected with HA-SNX27 (A and B) or HA-β2AR (C and D). (E–H) HeLa cells were transfected with wild-type strumpellin-myc (E and G) or with strumpellin-myc V626F (F and H), as well as HA-SNX27 (E and F) or HA-β2AR (G and H). Strumpellin knock-down was confirmed by immunoblotting (Supplementary Fig. 5).