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. 2013 Jun 5;33(23):9743–9751. doi: 10.1523/JNEUROSCI.0499-13.2013

Figure 1.

Figure 1.

Chocolate increases cataplexy in orexin KO mice. A, Palatable foods increase cataplexy during the dark period; chocolate increases the number of cataplexy bouts 8.1-fold compared with regular chow alone (10% sucrose solution: n = 7; peanut butter: n = 7; chocolate: n = 11). B, Orexin KO mice prefer to eat chocolate over regular chow (n = 9). C, Typical examples of EEG theta power (4–9 Hz), EEG delta power (0.5–4 Hz), EMG, and hypnogram of an orexin KO mouse in the absence (top) or presence (bottom) of chocolate demonstrating the large increase in cataplexy with chocolate. Cataplexy bouts are highlighted in gray. D, Chocolate increases cataplexy across the dark period (n = 11). E, Chocolate consumption is not correlated with cataplexy (n = 11). *p < 0.05; **p < 0.01; ***p < 0.001.