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Comparison of WIPC in the WASp-bound and unbound states. In ribbons/stick style, the conformation of a WIP peptide (residues 451–485) bound to neuro-WASp (12) is shown as a superposition of five low-energy structures. For clarity, side chains are shown for one conformer only. Below is a schematic representation of unbound WIPC obtained in this study, showing unstructured linkers (thin lines) and regions of structural tendency (cylinders).
