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Baseline biomarker summary
| Baseline biomarker | Threshold | Median PFS
|
Median OS
|
||||
|---|---|---|---|---|---|---|---|
| Above threshold, d (N) | Below threshold, d (N) | P | Above threshold, d (N) | Below threshold, d (N) | P | ||
| CYFRA 21-1 | 2.3 ng/mL | 44 (18) | 57 (14) | 0.0016 | 72 (18) | 242 (14) | 0.007 |
| NSE | 15 ng/mL | 44 (20) | 68 (12) | 0.0044 | 90 (20) | 242 (12) | 0.0088 |
| CTC | 12/7.5 mL | 37 (16) | 59 (12) | 0.0183 | 67 (16) | NR (12) | 0.0057 |
Abbreviations: N, number of patients; NR, not reached.
