Skip to main content
. Author manuscript; available in PMC: 2013 Jul 18.
Published in final edited form as: Nanotoxicology. 2010 Dec 22;5(4):592–605. doi: 10.3109/17435390.2010.541292

Figure 5. Cytotoxicity of homogenized and wet-milled nanoART on monocytes and MDM.

Figure 5

Monocytes and MDM were loaded with homogenized (H1008, H2014) or wet milled (M1002, M2006) formulations at 0.1 mM and 0.5 mM. Following drug loading, toxicity was assessed over 48 hrs by alamarBlue™ assay. Control consisted of untreated cells. Compared to homogenized formulations, wet milled IDV and RTV were significantly more toxic to monocytes and MDM. Comparison of milled nanoART with all homogenized formulations gave similar results. For each experimental condition, n = 3. Figure shown is representative of 3 independent experiments (#P<0.05, *P<0.01; **P<0.001).