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. Author manuscript; available in PMC: 2013 Jul 18.
Published in final edited form as: Nanotoxicology. 2010 Dec 22;5(4):592–605. doi: 10.3109/17435390.2010.541292

Figure 8. Effect of nanoART on tight junction proteins and TNF-α expression.

Figure 8

(A) Exposure of HBMEC to monocytes carrying nanoART did not alter expression of ZO-2 and occludin in HBMEC. 1: control HBMEC (not treated with nanoformulations); 2: HBMEC exposed to control monocytes; 3, 4, 5, 6 are HBMEC exposed to monocytes loaded with H1008, H2014, H1013b and H2013 respectively. All nanoART were at 0.1 mM concentration. M1002 (B) and M2006 (C) increased monocytes TNF-α expression (#P<0.05, **P<0.001), while all other nanoART did not induce TNF-α expression when compared to controls. Data shown are representative of 3 independent experiments.