Fig. 2.
In vivo siRNA-AAH microinjection into the implantation site causes intrauterine growth restriction. The implantation sites (mesometrial triangles) of GD17 pregnant Long Evans rats were microinjected with siRNA-AAH or siRNA-Scr (See Methods), and 24 hours later, the (A) pups and placentas were harvested to examine effects on body growth. The graphs depict the mean ± S.E.M. corresponding to (B) pup weight, placental weight or (C) pup length. Inter-group comparisons were made using Student t-tests.