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. Author manuscript; available in PMC: 2013 Jul 18.
Published in final edited form as: Cancer Res. 2008 Apr 1;68(7):2233–2240. doi: 10.1158/0008-5472.CAN-07-5278

Figure 5.

Figure 5

Effects of TNFα in the bystander effects. A. Combined treatment of NHLF with TNFα (20 ng/ml) and IL1β (2 ng/ml) induced COX-2 expression as determined by Western blot analysis. B. EMSA of NF-κB DNA-binding activity in control and bystander cells, with or without anti-TNF mAb (5 μg/ml) in the medium. C. Effects of treatment with the inhibitory anti-TNF mAb (5 μg/ml) on COX-2 levels in control, α-irradiated and bystander cells. D. Clonogenic survival assay of NHLF after indicated treatment with and without inhibitory anti-TNF mAb (5 μg/ml). Data are pooled from three independent experiments. Bar represents ± SD.