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. Author manuscript; available in PMC: 2014 Jul 1.
Published in final edited form as: J Neuropathol Exp Neurol. 2013 Jul;72(7):708–715. doi: 10.1097/NEN.0b013e31829a25b9

Figure 1.

Figure 1

Amyloid-β (Aβ) immunohistochemistry demonstrating cerebral amyloid angiopathy (CAA) severity scale in meningeal blood vessels. (A) “Stage 1” CAA in a meningeal vein with a focal aggregation of Ab. (B) “Stage 2” CAA in meningeal veins. In this photomicrograph the subarachnoid space is a “V”-shaped wedge in the middle; some leptomeningeal blood vessels show patchy CAA (red arrow) but others are unstained (green arrow). (C) “Stage 3” CAA in meningeal vessels. In the area between the red arrows the Ab immunohistochemistry in the blood vessel walls is consistently dark and nearly uniformly distributed. Scale bars: A, C, 200 mm; B, 50 mm.

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