Table 4.
Smoking | CYP2E1 genotype
|
||||||
---|---|---|---|---|---|---|---|
dose (py) | cl/cl | cl/c2 | cl/c3 | c2/c3 | c4/c4 | ||
Caucasians | ≤ 24 | Cases | 35 | 0 | 0 | 0 | 0 |
Controls | 142 | 11 | 1 | 0 | 0 | ||
|
|||||||
OR (95% CI) | undefined (P = 0.127)a | ||||||
> 24 | Cases | 69 | 7 | 0 | 0 | 1 | |
Controls | 66 | 3 | 1 | 0 | 0 | ||
|
|
||||||
OR (95% CI)b | 1.0 | 0.59 (0.15–2.40) | |||||
African Americans | ≤ 24 | Cases | 15 | 0 | 0 | 0 | 0 |
Controls | 112 | 1 | 10 | 0 | 0 | ||
|
|||||||
OR (95% CI) | undefined (P = 0.598)a | ||||||
> 24 | Cases | 37 | 0 | 5 | 1 | 0 | |
Controls | 38 | 0 | 7 | 0 | 0 | ||
|
|
||||||
OR (95% CI)b | 1.0 | 0.69 (0.19–2.46) | |||||
Combined | ≤ 24 | Cases | 50 | 0 | 0 | 0 | 0 |
Controls | 254 | 12 | 11 | 0 | 0 | ||
|
|||||||
OR (95% CI) | undefined (P = 0.033)a | ||||||
> 24 | Cases | 106 | 7 | 5 | 1 | 1 | |
Controls | 104 | 3 | 8 | 0 | 0 | ||
|
|
||||||
OR (95% CI)c | 1.0 | 0.70 (0.26–1.84) |