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. Author manuscript; available in PMC: 2013 Jul 18.
Published in final edited form as: J Pain. 2011 Sep 25;12(12):1219–1229. doi: 10.1016/j.jpain.2011.06.007

Table 2b.

correlation and connectivity analyses: Fibromyalgia patients

Region Cluster size (# of voxels) R values z-score (peak value) Coordinates (MNI)
x y z
Negative correlation between pain (%BR) and BOLD response (FM group)
R brainstem 72* −.87 4.59 12 −28 −18
Positive correlation between anxiety scores (STPI A) and BOLD response (FM group)
R inferior frontal gyrus/insula/medial frontal gyrus 2165 .86 4.39 50 26 12
R superior frontal gyrus 113 .75 3.49 14 30 56
R putamen 230 .82 4.01 24 −4 2
L superior temporal gyrus 415 .83 4.15 −44 −24 −2
L superior frontal gyrus 123 .80 3.85 −12 −10 70
L middle frontal gyrus 100 .80 3.84 −36 40 −8
L middle/inferior frontal gyrus 302 .77 3.63 −34 28 22
L putamen 165 .77 3.58 −26 −10 −12
Negative correlation between anxiety scores (STPI A) and BOLD response (FM group)
R/L rectus gyrus 114 −.76 3.55 0 50 −20
R/L superior frontal gyrus 234 −.85 4.33 −2 60 36
R temporal inferior gyrus/fusiform gyrus 134 −.62 3.94 50 −38 −26
Positive correlation between MFI scores and BOLD response (FM group)
L insula/putamen 187 .74 3.36 −38 10 −6
Negative correlation between MFI scores and BOLD response (FM group)
R temporal inferior gyrus/fusiform gyrus 116 −.76 3.54 52 40 −24
R orbitofrontal cortex/middle frontal gyrus 138 −.83 4.08 24 38 −18
L cerebellum, anterior lobe 110 −.75 3.48 −20 −44 −30
fc analysis – fc during inhibition between right inferior temporal/fusiform gyrus (SR) and TR: FM > HC
TR: R/L superior/medial frontal gyrus 4.08 / 128 4 34 36
TR: L supplementary motor area/superior frontal gyrus 3.76 / 135 −10 16 54

%BR = percentage body regions in pain, fc = functional connectivity, FM = fibromyalgia, HC = healthy controls, SR = seed region, TR = target region, L = left, R = right

*

Cluster fell slightly short of the apriori determined cluster extent of 92 voxels.