TABLE IV.

Parameter Values

Symbol	Parameter	Value
Birth/death
µE	Turnover time of epithelial cells	12hrs [40]
µT	Time a T cell remains active	5days [47]
µM0	Time a macrophage remains active	75 days
µd	Time a dendritic cell remains active	1 day [43]
µdL	Time a sDC remains active	1 day [43]
µce	Probability that pEcell is killed by Inflammatory factors
pT	Average number of daughter cells produced by a proliferating T cell	500 [49]
pTr	Average number of daughter cells produced by a proliferating nTreg	0
Migration
∈r	Average number of monocytes recruited by a single eDC, Ml, or pEcell	10
∈t	Average number of resting T cells recruited by a single eDC, Ml, or pEcell	10
βP	Probability that bacteria will enter the lumen upon contact with a pEcell	1
Contact/interactions
αT	Probability of memory T cell stimulation	1
αTr	Probability of memory nTreg stimulation	1
νT	fraction of active T cells that become memory T cells	0.1 [50]
ν 12	Probability that M1 switches to M 2	${\left(\frac{a_{1}R}{a_{1}R+i_{1}N}\right)}^{y_1}$
ν21	Probability that M2 switches to M1	${\left(\frac{a_{2}N}{i_{2}R+a_{2}N}\right)}^{y_2}$
a 1	co-efficient of ν 12 for activators	1
i 1	co-efficient of ν 12 for inhibitors	1
Y 1	exponent of ν 12	4
a 2	co-efficient of ν 21 for activators	1
i 2	co-efficient of ν 21 for inhibitors	4
y 2	exponent of ν 21
υνBM	probability that microfloral bacteria induces inflammatory phenotype in macrophages	0
νBD	probability that microfloral bacteria induces inflammatory phenotype in dendritic cells	0
νBs	probability that microfloral bacteria induces inflammatory phenotype in ‘sampling’ dendritic cells	0
νEC	Probability that EC transitions to pEcell upon contact with inflammatory factors	0.05
νEB	Probability that EC is damaged by microbial toxins	1 [51]