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. Author manuscript; available in PMC: 2013 Jul 18.
Published in final edited form as: Neuroimage. 2008 Feb 7;40(4):1772–1781. doi: 10.1016/j.neuroimage.2008.01.039

Table 7.

Changes in brain activation relating to age and/or neurophysiological parameters

Talairach coordinates in
MNI space
Region Side x y z Z-value Partial correlation
with age2 (r2)		 Partial correlation with
neurophysiologya (r2)
(i) BG and age2/IHI40c
Primary motor cortex I 40 −20 56 3.95 (+) 0.33 (+) 0.38
I 42 −18 50 3.79 (+) 0.31 (+) 0.32
(ii) BF and age2/IHI40c
Primary motor cortex I 42 −20 64 3.91 (+) 0.02 (+) 0.46
(iii) BG and age2/I50
Ventrolateral premotor cortex/BA44 C −42 12 20 4.54 (+) 0.02 (+) 0.52
I 46 14 24 4.95 (+) 0.03 (+) 0.57
I 50 16 16 4.65 (+) 0.03 (+) 0.45
(iv) BF and age2/I50
Ventrolateral premotor cortex/BA44 C −46 22 20 3.12 (+)0.10 (+) 0.35
C − 54 22 22 3.13 (+) 0.17 (+) 0.27
I 46 22 26 3.09 (+) 0.05 (+) 0.31

Voxels in which the variability in parameter estimates BG or BF can be explained by age2 and/or a neurophysiological parameter (after orthogonalisation with respect to age2). The relative contribution of each explanatory variable is given as the r2. Voxels are significant at P<0.05, corrected for multiple comparisons within a priori ROIs (see Methods section). The direction of the correlation (+ or −) is given next to the value for the coefficient of determination, r2.

C = contralateral, I=ipsilateral to hand movement, BA=Brodmann area, BG=parameter estimate for the main effect of hand grip, BF=parameter estimate for the force covariate (see Methods section).

a

After correction for age2.