Table 2. Coagulation parameters from hepatosplenic schistosomiasis patients with different patterns of periportal fibrosis.
| Characteristics | Controls (C) | Hepatosplenic Schistosomiasis Patients | p-value | |||||
| Overall | D fibrosis pattern | E+F fibrosis pattern | Overall vs. C | D vs. C | E+F vs. C | D vs. E+F | ||
| Subjects (n) | 29 | 55 | 17 | 38 | - | - | - | - |
| Platelets Count (×109/L) | 261.1±9.8 | 128.4±12.7 | 146.6±23.1 | 120.3±14.0 | <0.0001 | <0.0001 | <0.0001 | 0.1112 |
| INR | 1.01±0.02 | 1.44±0.06 | 1.38±0.09 | 1.47±0.07 | <0.0001 | 0.0028 | <0.0001 | 0.4828 |
| TT (Seconds) | 11.9±0.2 | 13.8±0.2 | 13.56±0.4 | 13.85±0.3 | <0.0001 | 0.0001 | <0.0001 | 0.4770 |
| PTT (Seconds) | 31.1±0.6 | 37.9±1.5 | 36.4±1.9 | 38.6±2.0 | 0.0012 | 0.0510 | 0.0010 | 0.3969 |
| Fibrinogen (mg/dL) | 342.9±21.0 | 267.5±9.9 | 263.4±15.6 | 269.4±12.7 | 0.0002 | 0.0045 | 0.0007 | 0.9770 |
| Factor II (%) | 92.7±3.3 | 66.6±2.3 | 67.8±4.2 | 66.0±2.8 | <0.0001 | <0.0001 | <0.0001 | 0.6377 |
| Factor VII (%) | 84.8±4.1 | 49.9±2.4 | 56.6±4.2 | 46.9±2.7 | <0.0001 | <0.0001 | <0.0001 | 0.0839 |
| Factor VIII (%) | 120.2±6.5 | 90.5±4.2 | 96.3±8.2 | 87.9±4.8 | 0.0001 | 0.0164 | <0.0001 | 0.3238 |
| Factor IX (%) | 100.1±3.3 | 59.9±2.5 | 65.3±4.5 | 57.5±2.9 | <0.0001 | <0.0001 | <0.0001 | 0.1375 |
| Factor X (%) | 88.8±3.7 | 63.8±3.7 | 59.1±7.4 | 65.91±4.3 | <0.0001 | 0.0001 | 0.0001 | 0.4842 |
| Protein C (%) | 100.1±2.2 | 65.6±2.9 | 74.5±5.1 | 61.6±3.3 | <0.0001 | <0.0001 | <0.0001 | 0.0124 |
| Antithrombin IIa (%) | 112.0±3.4 | 92.8±3.5 | 96.0±8.8 | 91.3±3.3 | <0.0001 | 0.0319 | 0.0007 | 0.4560 |
Values are expressed as mean±Standard Error (SE). Unpaired Student's t test or one-way ANOVA followed by Fisher's PLSD post test.