Table 2. Results obtained from SVM prediction system.
Putative Loops | Prediction | Probability | Prediction | Probability |
WT allele | WT allele | Expanded allele | Expanded allele | |
MR – exon 1 | L | 0.53 | L | 0.68 |
MB – exon 1 | NL | 0.96 | NL | 1 |
prom – exon 1 | NL | 1 | NL | 1 |
MR – intron 2 | L | 0.84 | L | 0.87 |
MB – intron 2 | L | 0.9 | L | 0.92 |
prom – intron 2 | L | 0.91 | L | 0.92 |
exon 1 – intron 2 | NL | 0.52 | NL | 0.51 |
The first column lists the possible combination of CTCF binding sites, as already reported (Figure 2). Columns 2 and 3 report the prediction (L = predicted loop, NL = predicted non-loop) and the probability of WT allele for each putative loop, while columns 4 and 5 report results of expanded CGG allele (>200 repeats). Probability is an accuracy index of prediction, higher is its value more confident is the prediction. In bold are reported the more probable loops.