Table 3. Genotype and allele distribution of MTHFR SNPs in relation to sperm motility.
| SNP/rsID | Genotype | Motility<30% | Motility>30% | 11vs12 | 11vs22 | 11vs(12+22) | 22vs12 | 22vs(12+11) | 11vs12vs22 | 1vs2 |
| 203G>A (rs2066472) | GG(11) | 186(100) | 277(98.93) | 1.0 | 0.52 | 0.28 | 1.0 | 0.52 | 0.37 | 0.16 |
| GA(12) | 0(0) | 1(0.36) | ||||||||
| AA(22) | 0(0) | 2(0.71) | ||||||||
| G(1) | 372(100) | 555(99.11) | ||||||||
| A(2) | 0(0) | 5(0.89) | ||||||||
| 1298A>C (rs1801131) | AA(11) | 29(25.66) | 77(25.67) | OR = 1.01(CI = 0.60–1.7)P: 1.0 | 0.98(0.52–1.83)0.92 | 1.00(0.61–1.64)1.0 | 1.04(0.60–1.79)0.89 | 1.03(0.61–1.74)0.92 | 0.99 | 0.99(0.73–134)1.0 |
| AC(12) | 59(52.21) | 155(51.67) | ||||||||
| CC(22) | 25(22.12) | 68(22.67) | ||||||||
| A (1) | 117(51.77) | 309(51.5) | ||||||||
| C(2) | 109(48.23) | 291(48.5) | ||||||||
| 1793G>A (CM056008 NOIATAUM_DMCH) | GG(11) | 50(67.57) | 126(78.75) | 1.87(0.96–3.63)0.06 | 1.44(0.40–5.13)0.73 | 1.78(0.69–3.30)0.07 | 1.3(0.33–5.04)0.75 | 0.80(0.23–2.82)0.75 | 0.17 | 1.59(0.94–2.69)0.08 |
| GA(12) | 20(27.03) | 27(16.88) | ||||||||
| AA(22) | 4(5.41) | 7(4.38) | ||||||||
| G(1) | 120(81.08) | 279(87.19) | ||||||||
| A(2) | 28(18.92) | 41(12.81) | ||||||||
| Intronic (rs3818762) | CC(11) | 24(30.38) | 61(37.42) | 1.50(0.80–2.81)0.20 | 1.18(0.57–2.42)0.65 | 1.37(0.77–2.44)0.28 | 1.27(0.64–2.52)0.49 | 1.06(0.57–1.98)0.86 | 0.44 | 1.13(0.77–1.65)0.54 |
| CG(12) | 36(49.37) | 61(37.42) | ||||||||
| GG(22) | 19(24.05) | 41(25.15) | ||||||||
| C(1) | 84(53.16) | 183(56.13) | ||||||||
| G(2) | 74(46.84) | 143(43.87) |