Table 1. Demographic and clinical characteristics of Alzheimer’s disease patients (AD) and controls (C).

	Serum donors database		CSF donors database
	AD (n = 45)	C (n = 42)	AD (n = 37)	C (n = 29)
Age (years)	70.0±7.5	68.7±7.4	69.3±7.4	71.1±5.8
Gender (% male)	33.3	33.3	40.5	51.7
APOE (% ε4)	58.5	15.2	52.9	16.7
	(n = 41)	(n = 33)	(n = 34)	(n = 12)
MMSE	19.7±4.4	29.2±0.8	19.6±5.2	28.8±1.4
	(n = 44)	(n = 37)	(n = 37)	(n = 24)
ADAS-Cog	27.0±8.3	8.8±2.9	24.7±10.8	8.5±3.6
	(n = 30)	(n = 25)	(n = 20)	(n = 11)
CSF Aβ42 (pg/mL)	499±177	999±322	520±193	951±327
	(n = 44)	(n = 36)	(n = 36)	(n = 23)
CSF T-tau (pg/mL)	786±381	288±132	744±377	300±109
	(n = 44)	(n = 36)	(n = 36)	(n = 23)
Serum Aβ-IgG (OD)a	0.569±0.2	0.463±0.2
	(n = 45)	(n = 42)
CSF Aβ-IgG (OD)b			0.449±0.2	0.348±0.2
			(n = 37)	(n = 29)

Values are mean ± standard deviation. For gender and APOE status, percentages per group are given. ADAS-Cog - Alzheimer Disease Assessment Scale-Cognitive Subscale (range 0–70 errors); MMSE - Mini Mental Status Examination (range 0–30 points); OD - optical density.

^aDiluted 1∶100.

^bDiluted 1∶1.