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| IC50 (nM) | ||
| HIV strains | TMC125 | IPK1 |
| WT | 1.4 | 24 |
| MDRC4 | 6.8 | 199 |
| K103N | 1.8 | 1777 |
| Y181C | 5.9 | >10000 |
| K103N/Y181C | 19.3 | >10000 |
| V106A | 1.3 | 1.6 |
Antiviral activity of IPK1 and TMC125 compounds against defined reverse transcriptase resistant mutations using the Monogram Bioscience experimental assay.
