Table 3. Multivariate logistic regression model for LDUO.

Characteristic	OR	CI 95%	P
Detectable HIV viral load	2.86	0.78–9.36	0.23
BMI	1.39*	1.06–1.82	0.018
Triglycerides	1.002	0.99–1.01	0.66
HOMA-IR higher than 2.6	4.41	1.14–16.99	0.03
3TC use	0.86	0.61–1.21	0.39
EFV length of exposure	2.38	0.24–22.08	0.46
LPV length of exposure	1.86	0.18–18.53	0.59
CD4 count less than 200 cells/mL	5.57	0.55–55.9	0.14

Hosmer-Lemeshow test: 0.530. R Nagelkerke: 0.240.

Abbreviations: liver damage of uncertain origin (LDUO), Odds ratio (OR), confidence interval (CI), human immunodeficiency virus (HIV), body mass index (BMI), Homeostasis model assessment-insulin resistance (HOMA-IR), lamivudine (3TC), efavirenz (EFV), lopinavir (LPV).

^*The BMI OR shows the risk of developing LDUO per unit increase in BMI.