Skip to main content
. 2013 Jul 18;8(7):e68694. doi: 10.1371/journal.pone.0068694

Figure 4. Barrier dysfunction is attenuated in S100A9 knockout mice undergoing a 2-hit lung injury model.

Figure 4

Total protein levels (A), immunoglobulin M (IgM) content (B) and neutrophil counts (C) in bronchalveolar lavage fluid of wild-type (WT) and S100A9 knockout (KO) mice. Animals were spontaneously breathing (C), high tidal mechanically ventilated (HVT MV), exposed to LPS followed by spontaneously breathing (LPS) or exposed to LPS followed by HVT mechanical ventilation (HVT MV+LPS). Data represent means (SEM) of 6–8 mice per group. **p<0.01 WT versus KO, ###p<0.001, ##p<0.01, #p<0.01 versus WT C. §§§p<0.001 versus LPS-only. +++p<0.001, ++p<0.01 versus HVT MV-only.