Table 2. S100A8/A9 in non-overstretched lung areas.
| Healthy | LPS-exposed | |||||||
| LVT WT | LVT KO | LVT WT | LVT KO | |||||
| Total protein (µg/ml) | 85 [17] | 64 [17] | 131 [15] | 164 [12] | ||||
| IgM (ng/ml) | 58 [13] | 30 [5] | 107 [11] | 126 [18] | ||||
| Neutrophils (×104/ml) | 4.1 [1.8] | 2.7 [0.8] | 25 [2.9] | 25 [2.9] | ||||
| IL-6 (pg/ml) | 206 [30] | 204 [38] | 532 [56] | 620 [63] | ||||
| KC (pg/ml) | 135 [26] | 189 [35] | 1382 [342] | 1767 [518] | ||||
| MIP-2 (pg/ml) | 81 [17] | 57 [19] | 1436 [439] | 1093 [266] | ||||
| IL-1β (pg/ml) | 62 [8] | 57 [18] | 152 [9] | 201 [35] | ||||
| TNF-α (pg/ml) | B.D. | B.D. | 614 [64] | 386 [77] | ||||
Total protein, immunoglobin M (IgM), neutrophil influx, cytokines and chemokines in bronchoalveolar lavage fluid of wild-type (WT) and S100A9 knockout (KO) mice. Animals with healthy lungs or with pre-existing lung injury induced by lipopolysaccharide exposure were ventilated for 5 hours with low tidal volumes (LVT) (∼7.5 ml/kg). Data represent mean (SEM) of n = 6–8 mice/group. Below detection limit: B.D.