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. Author manuscript; available in PMC: 2014 Aug 1.
Published in final edited form as: Hum Genet. 2013 Apr 19;132(8):943–953. doi: 10.1007/s00439-013-1306-3

Table 2.

Demographic characteristics and their associations with UFs in the Right from the Start (2001-2012) and BioVU (2007-present) cohorts

A. Right from the Start Cohort
Characteristic n No UFs (n = 552) % UFs (n = 89) % OR* 95% CI
Lower Upper
Age
    Less than 25 58 10 2 1.00 Reference
    25 to 29 230 38 21 2.52 0.57 11.15
    30 to 34 239 37 42 5.12 1.20 21.94
    35-49 114 15 35 10.46 2.41 45.46
    Greater than or equal to 50 0 0 0 - - -
Body mass index
    Underweight (less than 20) 68 11 7 0.74 0.32 1.74
    Normal weight (20 to 24.9) 307 48 41 1.00 Reference
    Overweight (25 to 29.9) 152 24 21 1.04 0.59 1.83
    Obese (30 and above) 114 17 20 1.38 0.77 2.48
Study site
    North Carolina 195 28 54 2.20 1.39 3.47
    Tennessee 444 72 46 1.00 Reference
    Texas 2 <1 0 - - -
B.
Characteristic n No UFs (n = 997) % UFs (n = 997) % OR 95% CI
Lower Upper
Age
    Less than 25 18 1 <1 1.00 Reference
    25 to 29 62 5 1 0.59 0.16 2.22
    30 to 34 106 8 3 1.45 0.44 4.74
    35-49 508 21 31 5.35 1.73 16.47
    50-64 726 28 46 5.71 1.86 17.51
    Greater than or equal to 65 527 36 18 1.75 0.57 5.41
Body mass index
    Underweight (less than 20) 117 7 5 0.75 0.50 1.13
    Normal weight (20 to 24.9) 526 29 28 1.00 Reference
    Overweight (25 to 29.9) 556 29 31 1.08 0.85 1.36
    Obese (30 and above) 670 35 36 1.06 0.84 1.33

n = number, OR = odds ratio, CI = confidence interval