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. Author manuscript; available in PMC: 2015 Sep 1.
Published in final edited form as: Addict Biol. 2013 Mar 18;19(5):800–811. doi: 10.1111/adb.12048

Fig. 5.

Fig. 5

Effects of 100 and 200 μM LY-278,584 on responding for the self-infusion of 200 μM nicotine into the posterior VTA of Wistar rats. For the first 4 sessions, 200 μM nicotine alone was given. In sessions 5 and 6, LY-278,584 was co-infused with 200 μM nicotine. In session 7, only 200 μM nicotine was given. Data are the means ± S.E.M. Asterisks indicate that responses on the active lever were significantly higher than responses on the inactive lever for that session (p < 0.05). Plus symbols indicate that LY-278,584 significantly reduced responding for 200μM nicotine during sessions 5 and 6 compared to session 4 (p < 0.05).