Table 1.

Demographic, genetic, biochemical, and radiographic characteristics of the subjects

	CAA, n=42	AD/MCI, n=43	Healthy Elderly, n=50
Age, mean (±SD)	68 (10)	74 (7.4)	73.3 (7)
Female %	26	40	58
Hypertension %	57	67	28
Diabetes Mellitus %	10	14	0
Hyperlipidemia %	38	74	14
ApoE ε2, % allele frequency *	13	0	9
ApoE ε4, % allele frequency *	37	32	8
Global DVR, mean (±SD)	1.33 (0.2)	1.33 (0.27)	1.17 (0.13)
Lobar CMB count, median (IQR)	25 (5–57)	none	none
WMH volume in ml, median (IQR)	21 (9.9–32)	10.8 (5–16.3)	3.2 (2–5.6)
WMH percent of ICV, median (IQR)	1.2 (0.6–1.9)	0.68 (0.3–0.9)	0.2 (0.1–0.4)

^*APOE genotype was available in all CAA patients, 33 HE and 11 AD/MCI cases.

DVR = distribution volume ratio

CMB = cerebral microbleed

WMH = white matter hyperintensities

ICV = intracranial volume