Table 1.
Clinical and demographic characteristics of the patients and controls
| Characteristic | Patients | Controls |
|---|---|---|
| (n = 446) | (n = 491) | |
| aMean age (years) ± SD | 52.5 ± 9.9 | 51.8 ± 10.1 |
| Tumor stage | ||
| IA | 59 (13.2 %) | |
| IB | 61 (13.7 %) | |
| IIA | 59 (13.2 %) | |
| IIB | 53 (11.9 %) | |
| IIIA | 146 (32.7 %) | |
| IIIB | 52 (11.7 %) | |
| IVA | 9 (2.0 %) | |
| IVB | 7 (1.6 %) | |
| Histological grade | ||
| G1 | 85 (19.1 %) | |
| G2 | 141 (31.6 %) | |
| G3 | 96 (21.5 %) | |
| Gx | 124 (27.8 %) | |
| Histological type | ||
| Squamous cell carcinoma | 376 (84.3 %) | |
| Adenocarcinoma | 54 (12.1 %) | |
| Other | 16 (3.6 %) | |
| Pregnancy | ||
| Never | 47 (10.5 %) | 54 (11.0 %) |
| Ever | 399 (89.5 %) | 437 (89.0 %) |
| Oral contraceptive pill use | ||
| Never | 244 (54.7 %) | 275 (56.0 %) |
| Ever | 202 (45.3 %) | 216 (44.0 %) |
| Tobacco smoking | ||
| Never | 289 (64.8 %) | 328 (66.8 %) |
| Ever | 157 (35.2 %) | 163 (33.2 %) |
| Menopausal status | ||
| Premenopausal | 155 (34.8 %) | 186 (37.9 %) |
| Postmenopausal | 291 (65.2 %) | 305 (62.1 %) |
| HPV genotypes | ||
| 16 and 18 | 307 (68.8 %) | |
| 16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, and 68 | 346 (77.6 %) | |
aAge at first diagnosis