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. 2013 Jul 19;3:2233. doi: 10.1038/srep02233

Figure 1. Chemical characterization of H2O2-activatable PVAX nanoparticles.

Figure 1

(a) A schematic diagram of PVAX nanoparticle + synthesis and therapy for I/R. (b) 1H NMR spectrum of PVAX in CDCl3. 1H NMR in deuterated chloroform on a 400 MHz spectrometer: 7.0 ~ 7.3 (m, 3H, Ar), 5.3 (m, 2H OCH2-PhO-CH3), 4.1 ~ 4.2 (m, 4H, COOCH2CH), 3,8 (m, 3H, OCH3), 2.2 (m, 2H, C(CH2)3HO), 1.0 ~ 1.8 (m, 8H, Cyclic CH2). (c) Hydrolysis kinetics of PVAX under physiological conditions, N = 4/group. (d) A representative dynamic light scattering of PVAX nanoparticles suspended in PBS. (e) A representative SEM image of empty PVAX nanoparticles. (f) 1H NMR spectrum of PVAX after hydrolysis of 2 days in D2O. (g) Release kinetics of VA from PVAX.