Table 3.

Echocardiographic Parameters

	HIV−		HIV+		ANCOVA resultsa
Variable	MC− (n=41)	MC+ (n=37)	MC− (n=59)	MC+ (n=64)	HIV p	MC p	HIV*MC p
BSA (m2)	2.0±0.3	2.2±0.2	2.0±0.3	2.1±0.4	0.039	<0.001	0.203
HR (bpm)	63.1±9.7	67.7±11.5	64.6±12.2	65.9±12.3	0.656	0.059	0.288
LV structure
LVM-mm (g)	166.4±38.0	206.9±49.6	183.2±38.8	200.2±47.8	0.615	<0.001	0.058
LVMI (g/m2)	83.3±12.8	91.7±17.3	93.4±16.4	95.8±21.7	0.007	0.045	0.262
LV systolic function
EF (%)	62±6	62±6	59±6	61±7	0.022	0.405	0.535
FS (%)	31.3±6.5	33.1±4.8	33.7±6.2	34.7±6.0	0.093	0.161	0.532
LVET (ms)	300.8±21.8	291.2±28.7	291.1±32.9	283.5±33.9	0.056	0.060	0.827
S′ (cm/s)	8.9±1.3	8.4±1.5	8.1±1.0	8.1±0.9	0.003	0.133	0.174
LV diastolic function
E-wave (cm/s)	71.6±11.5	72.0±17.2	68.9±15.6	67.4±15.4	0.035	0.950	0.583
E/A ratio	1.59±0.41	1.51±0.48	1.52±0.52	1.29±0.44	0.026	0.027	0.230
E′ (cm/s)	13.1±2.4	12.0±2.3	12.4±2.3	11.6±2.3	0.105	0.005	0.795
E/E′	5.6±1.0	6.1±1.3	5.6±1.3	5.9±1.4	0.533	0.020	0.520
DT (ms)	199.2±36.2	199.3±38.0	199.7±36.9	202.9±35.6	0.556	0.832	0.739
IVRT (ms)	82.1±16.0	88.4±16.5	87.8±15.7	87.7±13.0	0.237	0.173	0.149

^aAdjusted for race.

HIV, human immunodeficiency virus; MC, metabolic complications; BSA, body surface area; HR, heart rate; LVM-mm, left ventricular mass measured by M-mode; LVMI, left ventricular mass index (LVM/BSA); EF, ejection fraction; LVET, left ventricular ejection time; FS, fractional shortening; S′, systolic myocardial velocity averaged from the lateral wall and septum; E′, myocardial velocity during early diastole averaged from the lateral wall and septum; DT, deceleration time; IVRT, isovolumic contraction time.