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. 2013 Aug;29(8):1117–1122. doi: 10.1089/aid.2013.0038

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Copyright 2013, Mary Ann Liebert, Inc.

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FIG. 3. — The effect of resistance to etravirine on replication capacity. (a) Association between the number of resistance-associated mutations (RAMs) to etravirine (ETR) and replication capacity. The mutations associated with resistance to ETR include V90I, A98G, L100I, K101EHP, V106I, E138AGKQ, V179DFT, Y181CIV, G190SA, and M230L [p=0.081 by one-way analysis of variance (ANOVA)]. (b) Association between HIV-1 susceptibility to ETR and replication capacity (p<0.001 by one-way ANOVA). (c) Association between the number of selected RAMs (including L100I, K101P, Y181C/I/V) to ETR and replication capacity (p<0.001 by one-way ANOVA).