TABLE 5.
Features of IC Compared to Non-IC Subjects Among 302 Patients With Crypto at UAB, 1996–2010
| Characteristic | IC N = 263 (%) | Non-IC N = 39 (%) | P Value |
|---|---|---|---|
| Serum CrAg ≥ 1:512 | 75 (29) | 5 (13) | 0.036 |
| SF CrAg ≥ 1:512 | 70 (27) | 7 (18) | 0.237 |
| Mean OP, cm H2O | 31 | 36 | 0.238 |
| Mean CSF WBC, cells/mm3 | 79 | 304 | <0.001 |
| Mean CSF glucose, mg/dL | 48 | 37 | 0.053 |
| Mean CSF protein, mg/dL | 133 | 182 | 0.332 |
| Permanent CSF shunt | 24 (14) | 11 (44) | <0.001 |
| 90-day mortality | 59 (22) | 4 (10) | 0.081 |
| 1-year mortality | 80 (30) | 6 (15) | 0.052 |
Abbreviations: IC, immunocompromised; CrAg, cryptococcal antigen; OP, opening pressure; CSF, cerebrospinal fluid; WBC, white blood cell.