TABLE 1.
Registered Clinical Trials Using Eliglustat Tartrate
| Trial | Phase | Subject No. | Design | Status |
|---|---|---|---|---|
| NCT01452542 | 1 | 22 | Pharmacokinetics of eliglustat tartrate in healthy subjects | Completed |
| NCT01357811 | 1 | 28 | Effects of eliglustat on the pharmacokinetics of digoxin | Completed |
| NCT01659944 | 1 | 14 | Effects of eliglustat on the pharmacokinetics of metoprolol | Completed |
| NCT00358150 | 2 | 22 | Open label, type 1 Gaucher patients naïve to treatment | Completed fifth year of extension trial |
| ENGAGE NCT00891202 | 3 | 40 | Randomized control, double -blind, treatment -naïve type 1 Gaucher patients | Primary treatment period completed |
| ENCORE NCT00943111 | 3 | 160 | Randomized, type 1 patients stabilized on ERT, imiglucerase versus eliglustat | Primary treatment period completed |
| EDGE NCT01074944 | 3 | 171 | Single- versus twice-daily dosing of eliglustat | Ongoing |