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. Author manuscript; available in PMC: 2014 Sep 1.
Published in final edited form as: Bone. 2013 May 28;56(1):83–90. doi: 10.1016/j.bone.2013.05.014

Table 1.

Short-term reproducibility parameters: mean and standard deviation of baseline measures, root mean square of standard deviation (RMSSD), and root mean square of percent coefficient of variance (RMS%CV) of trabecular bone density, microstructure, and stiffness measurements based on registered and unregistered scans.

BV/TV Tb.N* (1/mm) Tb.Th* (mm) Tb.Sp* (mm) SMI Conn.D (1/mm3) Tb.BMD (mgHg/cm3) Tb.TMD (mgHg/cm3) Stiffness (kN/mm)
Baseline scan measurements
Mean ±SD 0.300 ±0.077 5.33 ±0.51 0.0754 ±0.0093 0.167 ±0.020 1.30±0.69 141±28 393±63 923±15 82±30
Unregistered baseline and follow-up scans
RMSSD 0.00718 0.141 0.000897 0.00297 0.144 10.255 4.462 7.850 7.853
RMS%CV 2.65% 2.49% 1.20% 1.76% 4.29% 7.49% 1.14% 0.85% 8.83%
Registered baseline and follow-up scans
RMSSD 0.00609 0.113 0.000687 0.00225 0.129 9.304 3.848 6.901 6.109
RMS%CV 2.37% 2.01% a 0.97% 1.33% 4.01% 7.01% 1.01% 0.75% a 6.48% b

Significant improvement from the unregistered comparison was indicated by

a

p<0.05;

b

p<0.005