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. Author manuscript; available in PMC: 2014 Sep 1.
Published in final edited form as: Neuroimage. 2013 Apr 13;78:75–82. doi: 10.1016/j.neuroimage.2013.04.012

Table 1.

Age-related effect of the GABA+/Cr, GABA+/NAA and Glx/Cr ratios in the frontal region and parietal region

Region of interest Age Effect Men + Women Age Effect Men Age Effect Women Age × Sex Effect
r P r P r P P
Frontal region (GABA+/Cr) -0.68 <0.001 -0.56 <0.001 -0.78 <0.001 0.03
Parietal region (GABA+/Cr) -0.54 <0.001 -0.51 <0.001 -0.56 <0.001 0.35
Frontal region (GABA+/NAA) -0.58 <0.001 -0.35 =0.01 -0.75 <0.001 0.001
Parietal region (GABA+/NAA) -0.49 <0.001 -0.34 =0.02 -0.64 <0.001 0.11
Frontal region (Glx/Cr) -0.47 <0.001 -0.37 =0.01 -0.58 <0.001 0.25
Parietal region (Glx/Cr) -0.37 <0.001 -0.31 =0.03 -0.42 =0.002 0.29

GABA = gamma-aminobutyric acid, Cr = total creatine, NAA = N-acetylaspartate, GABA+ = GABA plus co-edited macromolecules, Glx = glutamate+glutamine.