Table 1.

Treatment effects measured with log CFU, TTP, and C_T^a

Measurement	Group	Baseline		Days 0–7			Days 0–14
		n	Value	n	Change in value	P	n	Change in value	P
Log CFU	Group 1	14	5.51 (1.15)	11	−0.94 (1.76)	0.096	12	−0.97 (1.35)	0.018
	Group 2	15	5.91 (0.77)	14	−0.32 (1.18)	0.429	13	−0.97 (0.72)	0.009
	Group 3	14	5.42 (0.97)	13	+0.47 (1.41)	0.434	12	+0.17 (1.41)	0.994
	Group 4	14	5.48 (0.91)	12	+0.19 (0.56)	0.367	12	+0.39 (0.76)	0.385
	Group 5	13	6.34 (0.79)	12	−1.17 (0.82)	0.004	10	−1.84 (1.03)	0.0006
	Group 6	13	5.67 (1.17)	13	+0.08 (0.47)	0.860	12	−0.28 (0.71)	0.384
	Total	83	5.72 (1.00)	75	−0.26 (1.23)	0.2112	71	−0.55 (1.24)	0.0006
TTP	Group 1	15	115.6 (39.4)	15	+83.7 (73.7)	0.0005	15	+91.5 (77.5)	<0.0001
	Group 2	15	100.0 (20.6)	15	+53.7 (40.6)	0.0002	15	+78.1 (54.5)	<0.0001
	Group 3	15	120.4 (56.0)	14	+10.6 (62.2)	0.607	12	+6.68 (36.7)	0.835
	Group 4	15	125.7 (42.4)	15	−2.13 (23.2)	0.897	15	−11.3 (24.9)	0.423
	Group 5	15	124.3 (77.4)	14	+70.5 (50.9)	0.073	13	+151.1 (125.1)	0.004
	Group 6	15	110.1 (24.5)	15	−2.52 (21.9)	0.770	14	+13.2 (41.0)	0.365
	Total	90	116.0 (47.6)	88	+35.5 (59.3)	0.0002	84	+54.8 (86.8)	<0.0001
CT	Group 1	14	19.1 (4.57)	11	+2.33 (2.80)	0.331	14	+3.87 (5.75)	0.030
	Group 2	14	18.9 (3.81)	12	+1.06 (3.18)	0.476	15	+1.27 (3.32)	0.311
	Group 3	14	19.6 (3.54)	10	−0.92 (2.71)	0.181	12	+0.61 (3.86)	0.478
	Group 4	14	20.1 (4.45)	14	+0.77 (2.18)	0.628	14	+1.29 (3.60)	0.524
	Group 5	13	17.9 (3.27)	12	+0.91 (3.72)	0.425	11	+3.56 (2.63)	0.021
	Group 6	14	20.0 (3.34)	14	−0.87 (3.05)	0.277	15	+1.85 (5.58)	0.350
	Total	83	19.3 (3.88)	73	+0.55 (3.07)	0.6030	81	+2.06 (4.37)	0.0020

^aBaseline values are means ± standard deviations. All P values were calculated using unpaired Student's t test. n, number of patients with measurements.