Fig 1.

PlySs2 displayed activity against various species. Multiple strains of staphylococci (including MRSA, MSSA, and VISA), streptococci, enterococci, Listeria, bacilli, and lactobacilli were tested for susceptibility to PlySs2 activity. Escherichia and Pseudomonas were tested as Gram-negative controls. Log-phase cultures were exposed to 32 μg/ml PlySs2 for 30 min in PB (for 60-min readings) (see also Fig. S4 in the supplemental material). The final OD₆₀₀ of the treated samples was divided by the final OD₆₀₀ of the untreated samples to generate the normalized values. Complete lysis registered a ratio of ∼0.02. ST, serotype.