Table 1.

Measured and target serum free ceftaroline concentrations for simulations with a dose of 600 mg q12h

Parameter	Concn (mg/liter) at:				t1/2 (h)	AUC0–12a (mg·h/liter)
	1 h	4 h	7 h	12 h
Target	23	10.4	4.6	1.1	2.8	63.9
Measured	21.1 ± 4.9	7.6 ± 2.3	3.4 ± 1.3	1.6 ± 0.9	2.0 ± 0.7	68.4 ± 8.2

^aAUC_0–12, area under the concentration-time curve from time zero to 12 h.