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Pharmacokinetic analysis
| Time of blood sample collection after L-AmB infusion | Mean AmB plasma level (mg/liter) (SD) |
||
|---|---|---|---|
| Total patients (n = 34 for T6 and T24; n = 27 for day 7) | Patients who developed CTC grade 3 hypokalemia (n = 3) | Patients who developed invasive fungal disease (n = 3) | |
| T6 | 160 (72) | 237 (60.3) | 164 (19.7) |
| T24 | 49.5 (19.1) | 78 (6.0) | 49.3 (9.0) |
| 7 days from the start of infusion | 1 (1.1) | 1.1 (1.3) | 0.9 (0.2) |
