Fig 8.

SEVI enhances cellular uptake of N. gonorrhoeae in vivo. N. gonorrhoeae was preincubated with PBS alone or with SEVI fibrils (35 μg/ml) and then injected intravaginally into BALB/c mice. After 24 and 72 h, a vaginal lavage was performed, and the number of recovered viable bacteria was measured by CFU assay. Data represent bacterial counts from individual mice from a single representative experiment. A horizontal line denotes the mean bacterial count for each group of animals. Statistical significance was determined using the Mann-Whitney test (*, P < 0.05).