. Author manuscript; available in PMC: 2013 Jul 19.

Published in final edited form as: Cancer Epidemiol. 2011 Dec 6;36(2):e104–e110. doi: 10.1016/j.canep.2011.11.001

Table 4.

Associations between tagSNPs in IL23R and molecular subtypes of rectal cancer^a

			Controls	TP53 mutation				KRAS2 mutation				CIMP+

dbSNP ID	Common Name	genotype	N	N	OR	95% CI	P^b	N	OR	95% CI	P^b	N	OR	95% CI	P^b
rs10889675	88413 C > A	CC	583	172	1.00	ref.		103	1.00	ref.		34	1.00	ref.
		CA or AA	192	37	0.66	(0.46–0.94)	0.03	31	0.98	(0.66–1.46)	0.66	13	1.27	(0.68–2.39)	0.63

rs1884444	Gln3His	Gln/Gln	229	48	1.00	ref.		29	1.00	ref.		9	1.00	ref.
		Gln/His	370	125	1.51	(1.07–2.13)		65	1.24	(0.80–1.93)		24	1.46	(0.68–3.12)
		His/His	176	36	0.86	(0.55–1.34)	0.89	40	1.75	(1.08–2.83)	0.03	14	1.92	(0.83–4.42)	0.10

rs7539625	38962 G > A	GG	383	98	1.00	ref.		81	1.00	ref.		29	1.00	ref.
		GA or AA	390	111	1.22	(0.92–1.61)	0.47	53	0.65	(0.46–0.92)	0.02	18	0.63	(0.35–1.12)	0.10

rs7542081	69450 C > A	CC or CA	662	189	1.00	ref.		115	1.00			42	1.00	ref.
		AA	112	19	0.60	(0.37–0.98)	0.04	19	1.08	(0.67–1.75)	0.92	5	0.78	(0.32–1.92)	0.47

Adjusted for age, sex, center, race

P-value for trend; if dominant or recessive model, p-value for association is shown.