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. Author manuscript; available in PMC: 2014 Apr 1.
Published in final edited form as: Aging Cell. 2013 Apr;12(2):303–311. doi: 10.1111/acel.12055

Figure 4. Inhibition of B cell precursor growth is acquired with old age by ABC and is not seen with follicular (FO) B cells.

Figure 4

ABC, FO splenic B cells, or FO-like bone marrow B cells (2 × 105) from young or aged B6 mice were co-cultured in transwells with young adult bone marrow cells (1 × 106) as in Figures 1-3. IL-7 CFU data are cumulative from 4-12 experiments, with the exception of FO-like old cells used in 2 experiments. Statistical significance as shown: *, p<0.04; ****, p<0.0001.