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. Author manuscript; available in PMC: 2013 Jul 19.
Published in final edited form as: Biomaterials. 2011 May 18;32(24):5535–5542. doi: 10.1016/j.biomaterials.2011.04.046

Fig. 1.

Fig. 1

Macrophage recognition of PMMA particles involves MyD88-dependent TLRs and is independent of adherent endotoxin TNF-α production by RAW 264.7 murine macrophages cultured with (a) PMMA particles at a concentration of 0.03, 0.075, 0.15 and 0.30% v/v (n = 3); (b) PMMA particles, PMMA particles and Polymyxin B, LPS, LPS and Polymyxin B (4 independent trials, n = 3–6 per trial); (c) PMMA particles, PMMA particles plus a MyD88 inhibitory peptide, PMMA particles plus a control peptide. (2 independent trials, n = 3–6 per trial). % v/v = volume of particle (mL) per 100 mL of solution. * = P < 0.05, ** = P < 0.01.