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Effect of pretreatment with the NTR1 agonist PD149163 (PD; 0.5 mg/kg), antagonist SR48692 (SR; 0.3 mg/kg), or saline on lever-pressing behavior in SAM rats during 4–5 daily extinction sessions. The PD compound was administered 15 min prior to extinction session 1 but not 2–5. The SR compound was administered 15 min prior to 1–4 extinction sessions. *P < 0.05 versus corresponding saline groups. n = 23 (saline), n = 9 (SR), and n = 9 (PD).
