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. 2013 Aug;346(2):259–269. doi: 10.1124/jpet.113.205435

Fig. 11.

Fig. 11.

Schematic diagram showing cytochrome P450 (P450) metabolism of acetaminophen to the electrophilic metabolite, NAPQI, and the subsequent adduct-forming reactions with the enolate of 2-ACP or the GSH thiolate.