Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Ligand treatment increases SUMO(1)ylation of RXRα. (A) HuH-7 cells were transfected with F-RXRα and SUMO1 and treated with vehicle (veh; DMSO), 1 μM 9cRA, or 1 μM LG268 (LG) for 30 minutes; harvested; and immunoblotted as described in Fig. 1. (B) Graph of the averaged densitometry showing an increase in SUMOylation with either ligand. Data are presented as mean + S.E. and *P < 0.05, relative to the vehicle-treated control. Arrow denotes F-RXRα, and arrowhead denotes Su-F-RXRα.
