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1-Deoxysphingolipids in plasma of patients and healthy controls. Significantly elevated 1-deoxysphingolipid levels were found for patients carrying the SPTLC2-A182P mutation. Data are shown as means, with error bars representing SDs. SDs were calculated using 1-way analysis of variance with Bonferroni multiple correction. n.s. = not significant; SA = sphinganine; SO = sphingosine. ***p < 0.001; ****p < 0.0001.
