Table 4.

Best model Robust Odds Ratio with clamped hypothesis testing

	OR	95% CI
Male gender	2.23	1.58 - 3.16*
Serum Lactate >6.2 (mmol/L) 0-6 hrs.	2.01	1.46 - 2.76*
Vasopressor utilization 0-24 hrs.	1.97	1.41 - 2.74*
APACHE II >33	1.97	1.40 - 2.76*
NISS >34	1.77	1.31 - 2.39*
BMI >34	1.62	1.21 - 2.17*
Age >49 (yrs.)	1.50	1.10 - 2.04*
Clamped variables
PRBC administration >9.5 (U) 0-12 hrs.	1.91	1.32 - 2.76*
FFP administration >7.8 (U) 0-12 hrs.	1.00	0.78 - 1.86
Crystalloid administration > 12.4 (L) 0-12 hrs.	1.23	0.89 - 1.70

OR - Robust Odds Ratio estimates, CI - confidence interval, NISS - New injury severity score, BMI - Body mass index, PRBC - packed red blood cells, FFP - fresh frozen plasma, (U) - Units, (L) - Liters,

^*p<0.05